Supercritical CO₂ Extraction Machines and Equipment
The e-180, our largest supercritical CO₂ extractor.
A supercritical CO₂ extraction machine pumps carbon dioxide above its critical point, 31 °C (88 °F) and 73.8 bar (1,071 psi), through ground plant material in a pressure vessel. In that state the CO₂ dissolves oils, flavors and other non-polar compounds. A separator then drops the pressure, the CO₂ turns back to gas for recycling, and the extract collects with no residual solvent.
extraktLAB designs and builds its CO₂ extraction equipment in the USA, in Osceola, Wisconsin, from the M-2.5 for R&D up to the automated e-180, which processes 384–480 kg (846–1,058 lb) of biomass per day.
- Built in the USA
- Up to 345 bar (5,000 psi)
- GMP-ready, UL 508A
- 2.5 L to 4 × 20 L vessels

CO₂ extraction machine lineup
Every extractor runs sub- or supercritical CO₂, is built from 304 and 316 stainless steel, and is designed for GMP production. Pick a model by daily throughput, floor space and how much automation you want.
R&D extractor
M-2.5
Fully automated R&D system for method development, small batches, drying and sterilization trials.
- One 2.5 L (0.66 gal) extraction vessel
- 24–36 kg (52–79 lb) per day
- 55–345 bar (800–5,000 psi), −10 to 100 °C (14–212 °F)
- CO2, co-solvent or subcritical water
Manual extractor
M-120
Manual CO2 extraction machine built on the e-140 platform, with a simple on/off interface.
- One 20 L (5.28 gal) extraction vessel
- One 20 L collector and one 20 L recycler
- Operating pressure 345 bar (5,000 psi)
- 60 min cycle at 10% potency
Automated extractor
e-110
The smallest automated E-series machine, for pilot plants, labs and small producers.
- Two 5 L (1.32 gal) extraction vessels
- 48–60 kg (105–132 lb) per day
- 0–345 bar (0–5,000 psi), 25–100 °C (77–212 °F)
- Footprint 2.2 m² (24 sq ft)

Automated extractor
e-140
Our most popular CO2 extractor, with automated co-solvents and gradients. It connects to continuous automation.
- Two 20 L (5.28 gal) extraction vessels
- 192–240 kg (423–529 lb) per day
- 0–345 bar (0–5,000 psi), 0–100 °C (32–212 °F)
- Footprint 2.2 m² (24 sq ft)
Automated extractor
e-180
Our largest supercritical CO2 extractor. Several e-180s together reach 2,297 kg (5,064 lb) per day.
- Four 20 L (5.28 gal) extraction vessels
- 384–480 kg (846–1,058 lb) per day
- 0–345 bar (0–5,000 psi), 0–100 °C (32–212 °F)
- Footprint 4.5 m² (48 sq ft)
Specifications side by side
| Model | Extraction vessels | Throughput per day | Per cycle | Pressure | Temperature | L × W × H | Footprint | Weight | Control |
|---|---|---|---|---|---|---|---|---|---|
| M-2.5 | 1 × 2.5 L (0.66 gal) | 24–36 kg (52–79 lb) | 1–1.5 kg (2.2–3.3 lb) | 55–345 bar (800–5,000 psi) | −10 to 100 °C (14–212 °F) | 123 × 80 × 103 cm (48.375 × 31.615 × 40.688 in) | 0.97 m² (10.48 sq ft) | 365 kg (804 lb) | Fully automated |
| M-120* | 1 × 20 L (5.28 gal) | — | — | 345 bar (5,000 psi) | — | 251 × 86 × 183 cm (99 × 34 × 72 in) | 2.2 m² (24 sq ft) | — | Manual |
| e-110 | 2 × 5 L (1.32 gal) | 48–60 kg (105–132 lb) | 2–2.5 kg (4.4–5.5 lb) | 0–345 bar (0–5,000 psi) | 25–100 °C (77–212 °F) | 251 × 86 × 183 cm (99 × 34 × 72 in) | 2.2 m² (24 sq ft) | 1,361 kg (3,000 lb) | Fully automated |
| e-140 | 2 × 20 L (5.28 gal) | 192–240 kg (423–529 lb) | 8–10 kg (17.6–22 lb) | 0–345 bar (0–5,000 psi) | 0–100 °C (32–212 °F) | 251 × 86 × 183 cm (99 × 34 × 72 in) | 2.2 m² (24 sq ft) | 1,950 kg (4,300 lb) | Fully automated, co-solvent |
| e-180 | 4 × 20 L (5.28 gal) | 384–480 kg (846–1,058 lb) | 16–20 kg (35–44 lb) | 0–345 bar (0–5,000 psi) | 0–100 °C (32–212 °F) | 328 × 135 × 183 cm (129 × 53 × 72 in) | 4.5 m² (48 sq ft) | 2,812 kg (6,200 lb) | Fully automated, co-solvent |
Vessel sizes and throughput come from the extractor brochures. Throughput is at a 60 min cycle and 10% potency, and actual results vary with the material. The M-120 is available to order. Confirm the quoted equipment configuration.
Built into every E-series extractor
Process control
Programmable methods, automated extraction cycles, independent vessel control, cyclonic separation and data capture.
GMP records
Batch, operator and parameter tracking, instrument calibration and maintenance tracking, and clean in place.
Certifications
UL 508A listed. Vessels P.E. stamped to ASME Section VIII Div 2, PED compliant and CE marked, with Lloyd’s Register as notified body and CRN numbers available.
Regulatory
Designed for 21 CFR Parts 117, 211 and 177 and the Health Canada equivalents.
Scale-up
Add another extractor when you need more capacity, or connect the e-140 and e-180 to continuous automation.
Built in the USA
Designed and manufactured by United Science in Osceola, Wisconsin, with commissioning, training and maintenance from the same team.
How to choose CO₂ extraction equipment
Daily biomass
Start with how many kilograms you need to process per day, then match it to the specifications table. Leave room to add a second unit later.
Floor space and utilities
Check the footprint, ceiling height and electrical supply (208–230 V or 380 V versions), plus clearance around the machine.
Automation
Automated E-series machines cut labor per kilogram. The manual M-120 suits teams that want a simpler machine.
Product
Co-solvents and gradients on the e-140 and e-180 widen what you can extract, from flavors and colors to polyphenols.
CO₂ supply and support
Plan bulk CO₂ with our CO₂ supply equipment, and add commissioning, training, a GMP documentation package or a 12-month maintenance package.
Test your material first
Send us a sample. We run it on our extractors and send back the yield, the settings we used, and whether the process is worth taking further.
Applications
Food and flavor
Flavor and aroma extracts such as coffee, plus natural colors like carotenoids.
Nutraceuticals
Solvent-free botanical ingredients for supplements and functional foods.
Essential oils and cosmetics
Essential oils and skin care actives extracted at low temperature to keep volatile compounds intact.
Pharmaceutical and medical
High-purity extracts, plus supercritical CO₂ sterilization and decellularization.
Waste valorization
Recover oils and colors from food and agricultural by-products. See waste valorization.
Contract runs
No machine yet? We can run your material in Osceola during a feasibility study.
Frequently asked questions
What is a supercritical CO2 extraction machine?
It is a closed-loop system that raises CO2 above 31 °C (88 °F) and 73.8 bar (1,071 psi), passes it through ground plant material to dissolve oils and other compounds, then drops the pressure in a separator so the extract collects and the CO2 is recycled.
What size are the extraction vessels?
The M-2.5 has one 2.5 L (0.66 gal) extraction vessel, the e-110 has two 5 L (1.32 gal) vessels, the M-120 has one 20 L (5.28 gal) vessel, the e-140 has two 20 L vessels and the e-180 has four 20 L vessels.
How much biomass can a CO2 extractor process per day?
The automated E-series ranges from 48–60 kg (105–132 lb) per day on the e-110 to 384–480 kg (846–1,058 lb) per day on the e-180, at a 60 min cycle and 10% potency. Multiple e-180s reach 2,297 kg (5,064 lb) per day.
What pressure do CO2 extraction machines run at?
The E-series runs from 0 to 345 bar (0–5,000 psi). The M-2.5 R&D extractor covers 55–345 bar (800–5,000 psi).
Where are extraktLAB extractors made?
They are designed and built in the USA by United Science in Osceola, Wisconsin.
What does a CO2 extraction machine cost?
It depends on the model, automation, voltage, certifications and the support package. Email sales@extraktlab.com or call +1 651 600 0036 for a quote sized to your throughput.
Can I test my material before buying?
Yes. Send a sample and we run it on our extractors, then share the yield, the settings used and whether the process is worth taking further. See our feasibility studies.
Is a co-solvent system included as standard?
No. The M-2.5, e-110 and e-140 brochures describe co-solvent hardware as optional. Specify the method and required hardware with the equipment configuration.
Can the M-2.5 support method development for larger systems?
The M-2.5 brochure describes a method-development basis for larger E-series systems. Establish the feed, conditions, collection requirements and analytical endpoint for the intended scale; an R&D method alone is not a production-output guarantee.
Does the equipment footprint include all the space needed for installation?
No. Plan operating access, service clearance, height and ancillary equipment as well as the machine footprint. Confirm the site requirements for the specified configuration.
Is the M-120 available to order?
Yes. The M-120 is available to order. Discuss the configuration and project requirements with us.
Learn more about CO₂ extraction
- A complete guide to CO₂ extraction
How the process works step by step, and fractionation.
- Closed-loop CO₂ extraction
How the CO₂ is recovered and reused.
- Selecting CO₂ equipment for GMP
What to check before you buy.
- Ethanol vs CO₂: a critical analysis
Where each method fits.
- CO₂ supply equipment
Bulk CO₂ storage and delivery for the extractor.
- All extraction equipment
Extraction, distillation, filtration and chromatography.
Talk to us about your extraction project
Tell us your material, your daily throughput and your facility, and we will size the extractor and the support package for it.
sales@extraktlab.com · +1 651 600 0036