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E2Di

Part Number: #10-0174 (208-230V) | #10-0175 (380V)

The E2Di is the interface enabling complete containment of the active pharmaceutical ingredient from continuous extraction through distillation. It can be used as the base for extraction through isolate or extraction through complex compound separation.

The E2Di features sustainable and low-cost CO2 extraction, the system connects and automates transfer between the extraction system and a high-end dual-stage molecular distillation system, which also eliminates the need for ethanol and winterization.

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Features and Benefits
Specifications
More Information

E2Di FEATURES & BENEFITS

Eliminates Ethanol Winterization
Automation: Improve Efficiency & Accuracy
Reduced Cycle Time, Down Time, and Labor Costs
Full Containment of Extract from Extraction Through Distillation
Connects E-Series Extractors and clearSTILL-400
Better Yield: Preservation/Recovery of Aroma Profile

GMP COMPLIANCE:
Intended for use with distilled extracts
Process: Dissolution, mixing, precipitation, filtration, solvent recovery
Containment: Contained process
Lubricants: None in direct contact. No contact with process fluids
PLC GAMP5: Category 3
Materials Traceability & Manufacturers’ DOC for Contact Materials
Seals: PTFE, Vitron

SYSTEMS CLASSIFICATIONS:
E2Di unit:
Type: Direct Impact
Documentation: Commissioning, Qualification

Heater:
Type: Indirect Impact
Documentation: GEP Startup

Sweep Gas:
Type: Indirect Impact
Documentation: Commissioning, Qualification

CLEANABILITY:
Surface Finishes: 0.8 µm or better on all contact surfaces
Welds: Ground, argon purged;
Fittings: Combination of compression and sanitary
CIP: Sprayball, low point fluid exit
CIP Unit: External

General Specifications

Dimensions (inches)	L77.5″ x W50″ x H90″
Unit Weight (pounds)	650
Heat Load (kW)	3.5
Mobility	Leveling Casters

CERTIFICATIONS:
ETL UL 508A Stamped; CE; PED or ASME

REQUIRED, SOLD SEPARATELY (or start with EtoD System):
e-140 #10-0063 (240V) | #10-0099 (380V) OR
e-180 #10-0010 (240V) | #10-0147 (380V)
AND
clearSTILL-400 #10-0081 (240V) | #10-0099 (380V)

RECOMMENDED, SOLD SEPARATELY:
Heater, 1-zone, 6 kW, Recirculating Oil #80-0892 (240V) | #80-0891 (380V)

ALSO AVAILABLE, SOLD SEPARATELY:
Factory Acceptance Test (FAT); Site Acceptance Test (SAT); Design Qualification (DQ); Installation Qualification (IQ); Operational Qualification (OQ); GMP Documentation Package; Commissioning and Training Package; Maintenance Package (12 Months)

WARRANTY:
12 months for quality, labor, parts, and workmanship on United Science equipment.

The E2Di is an interface allowing for a pharmaceutical manufacturing solution within a continuous automation solution process. The contained system utilizes automation of high pressure CO2 extraction through wiped film distillation. This continuous flow system promotes increased yield with a reduced cycle time. The uniquely designed interface provides oil transfer, CO2 venting, and oil metering.

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