Application Notes
Access a wide range of application notes designed to support the nutraceutical, pharmaceutical, food, and beverage industries. Each document offers valuable insights into extraction techniques, process optimizations, and application-specific data, helping you achieve reliable and effective product outcomes.
DECELLULARIZATION WITH Subcritical CO2
Preserve the extracellular matrix (ECM) while removing cellular components to achieve >95% DNA removal while maintaining ECM integrity. Supercritical CO₂ (scCO₂) is a green, efficient method ideal for clinical-grade implants and research applications.
Subcritical Water CO2 Extraction
The integrated platform of Subcritical Water Extraction and Supercritical CO₂ extraction represents a transformative, solvent-free technology for the modern flavor and nutraceutical industries.
Dry Ice Blasting for Industrial Surface Cleaning & Preparation
Dry ice blasting is a revolutionary industrial cleaning technology that offers a cleaner, faster, and more sustainable approach compared to traditional methods.
Botanical Extract
Filtration
This application note details a multi-step approach to effectively remove solids, particulates, turbidity, and color from botanical extracts.
Supercritical CO2 Extraction of Carotenoids
Supercritical CO₂ extraction is a green, highly efficient, and superior technology for producing high-quality carotenoid extracts.
Authentic Coffee Flavor Extraction using scco2
This application note summarizes findings from an extraction study on Authentic Coffee Flavor concentrates utilizing solvent less supercritical CO2 extraction.
CO2 Extraction of Red Cedar & Spanish Cedar
This application note summarizes findings from an extraction study on Spanish Cedar, with insights relevant to Red Cedar processing.
Supercritical CO2 Extraction
of Frankincense
Essential Oil
This application note shows the proven method of extracting pure frankincense oil from the Boswellia Serrata plant biomass using the supercritical CO2 extraction method.
Beeswax Extraction Under Supercritical Carbon Dioxide Extraction
This application note shows how beeswax can be effectively extracted using extraktLAB’s E-140 which utilizes supercritical CO2 as the solvent.
WATER-SOLUBLE β-CYCLODEXTRIN-OLEORESIN PRODUCT DEVELOPMENT
This application note shows how cyclodextrin with oleoresin under supercritical CO2 conditions makes the molecules water-soluble and more bioavailable.
Green Lipped Mussel Oil Extracted Using Supercritical CO2 Technology
This application note outlines a solvent-free method for extracting Green Lipped Mussel Oil, ensuring high yield and purity for nutraceutical applications.
Removing Odors From Biomass Through Supercritical CO2 Technology
A glimpse into our CO2 extraction process that achieves odor-free biomass with minimal weight loss. Curious about how we did it and what’s next? The full study has all the answers.
Efficient Water Removal in Maple Syrup Production using Falling Film Evaporators
Streamline maple syrup production and enhances quality control. Learn how modern processing methods can improve your manufacturing efficiency and product consistency.
Bicalutamide Application Note
Supercritical CO₂ solid dispersions of bicalutamide reached about 9× faster dissolution than the crystalline drug, without organic solvents.
Lovastatin Application Note
This application note shows how supercritical CO₂ RESS micronizes lovastatin into sub-micron particles and why wetting and agglomeration control decide the dissolution gain.
Celecoxib Application Note
This application note shows how supercritical CO₂ antisolvent processing turns poorly soluble celecoxib into amorphous PVP solid dispersion nanoparticles with much faster dissolution.
Nifedipine Application Note
This application note shows how supercritical CO₂ RESS micronizes nifedipine without organic solvent, cutting particle size from 37 µm to 9 µm and raising 90-minute dissolution from 42% to 80%.
Fenofibrate Application Note
This application note shows how a supercritical CO₂ PGSS process makes a solvent-free lipid-based solid dispersion of fenofibrate, optimized at 78 °C and 80 bar for improved dissolution.
Lopinavir Application Note
This application note shows how supercritical CO₂-assisted spray drying forms lopinavir–cyclodextrin complexes with up to 129-fold higher aqueous solubility.
Cannabinoids Application Note
This application note shows how supercritical CO₂ loads cannabidiol into cellulose aerogels, releasing about 80% in simulated gastric fluid within 4 hours.